By E. Edward Bittar (Eds.)

ISBN-10: 1559382090

ISBN-13: 9781559382090

The fourth quantity of the ''Advances in Molecular and mobilephone Biology'' sequence. phone biology is a rapidly-developing self-discipline, bringing jointly many separate organic sciences. The interrelations of mobile constitution and serve as at molecular and subcellular degrees are the critical topic of the sequence

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K. C. WONG and J. 6. RATTNER Microinjection of antibodies into mouse oocytes that are naturally arrested at second meiotic metaphase, into eggs at first mitotic metaphase, or into immature oocytes at first meiotic metaphase does not affect anaphase chromosome separation. However prometaphase congression is disrupted if the antibody is injected into meiotic and mitotic eggs during interphase or prometaphase. Also the subsequent anaphase is aberrant. Taken together, these two sets of experiments indicate that the CENP proteins have some functions in the organization of the centromere and that their roles may begin prior to the onset of cell division.

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Cell 42, 291-296. Rattner. J . , & Lin, C. C. (1985). Chromosoma 92. 325-329. Rattner, J . , & Lin. C. C. (1987). Genome 29, 588-594. Rattner. J . B.. & Lin. C. C. (1988). The organization of the centromere and centromeric hetero- A . K. C. WONG and J. B. RATTNER 36 chromatin. In: Heterochromatin, Molecular and Structural Aspects (Verma. R. S.. ). pp. 203-227. Cambridge University Press, Cambridge. Rice, N. R.. & Straus. N . (1973). Proc. Natl. Acad. of Sci. USA 70, 35463550. Rieder. C. L. (1982).

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Advances in Molecular and Cell Biology by E. Edward Bittar (Eds.)


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